STK17A Antikörper (N-Term)

Produktnummer ABIN1888195

Produktdetails anti-STK17A Antikörper

Target: STK17A (serine/threonine Kinase 17a (STK17A))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STK17A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Kreuzreaktivität (Details): No cross responses to DRAK2, DAP or ZIP kinases.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Peptide corresponding to amino acids near the amino terminus of human DRAK1.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu STK17A

Target: STK17A (serine/threonine Kinase 17a (STK17A))

Andere Bezeichnung: DRAK1 (STK17A Produkte)

Synonyme: STK17A antikoerper, DRAK1 antikoerper, RDRAK1 antikoerper, serine/threonine kinase 17a antikoerper, serine/threonine kinase 17a L homeolog antikoerper, STK17A antikoerper, stk17a antikoerper, stk17a.L antikoerper

Hintergrund: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases.Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis.Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 for DAP kinase-related apoptosis-inducing protein kinases.DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain.Overexpression of DRAK1 induces apoptosis.DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities.DRAK1 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.

Molekulargewicht: 50 kDa

UniProt: Q9UEE5