CDC16 Antikörper (N-Term)

Produktnummer ABIN1888148

Produktdetails anti-CDC16 Antikörper

Target: CDC16 (Cell Division Cycle 16 Homolog (S. Cerevisiae) (CDC16))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC16 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: APC6 antibody was raised against an 18 amino acid peptide near the amino terminus of human APC6.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu CDC16

Target: CDC16 (Cell Division Cycle 16 Homolog (S. Cerevisiae) (CDC16))

Andere Bezeichnung: APC6 (CDC16 Produkte)

Synonyme: zgc:123264 antikoerper, F9K20.19 antikoerper, F9K20_19 antikoerper, anaphase promoting complex 6 antikoerper, 2700071J12Rik antikoerper, 2810431D22Rik antikoerper, APC6 antikoerper, ANAPC6 antikoerper, CUT9 antikoerper, cell division cycle 16 antikoerper, cell division cycle 16 L homeolog antikoerper, cell division cycle 16 homolog (S. cerevisiae) antikoerper, cell division cycle protein 16 homolog antikoerper, anaphase promoting complex 6 antikoerper, CDC16 cell division cycle 16 antikoerper, CDC16 antikoerper, cdc16.L antikoerper, cdc16 antikoerper, LOC100434328 antikoerper, APC6 antikoerper, Cdc16 antikoerper

Hintergrund: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis.APC6 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence.The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex.While little is known of APC6, it has been shown to interact with and is stabilized by CDC26 through an intermolecular TPR mimic composed of one helix from each protein.
Synonyms: Anaphase promoting complex 6, ANAPC6, CDC16

NCBI Accession: NP_003894

Pathways: Regulation of Actin Filament Polymerization