Transportin 3 Antikörper (N-Term)

Produktnummer ABIN1888081

Produktdetails anti-Transportin 3 Antikörper

Target: Transportin 3 (TNPO3)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Transportin 3 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid peptide from near the amino terminus of human TNPO3.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu Transportin 3

Target: Transportin 3 (TNPO3)

Andere Bezeichnung: TNPO3 (TNPO3 Produkte)

Synonyme: zgc:55409 antikoerper, tnpo3 antikoerper, MGC82948 antikoerper, TNPO3 antikoerper, DKFZp459J2330 antikoerper, IPO12 antikoerper, MTR10A antikoerper, TRN-SR antikoerper, TRN-SR2 antikoerper, TRNSR antikoerper, 5730544L10Rik antikoerper, C430013M08Rik antikoerper, C81142 antikoerper, D6Ertd313e antikoerper, Trn-SR antikoerper, mKIAA4133 antikoerper, transportin 3 antikoerper, transportin 3 S homeolog antikoerper, transportin-SR antikoerper, tnpo3 antikoerper, TNPO3 antikoerper, tnpo3.S antikoerper, Bm1_43850 antikoerper, LOAG_04608 antikoerper, Tnpo3 antikoerper

Hintergrund: TNPO3 is a member of the importin beta/transportin family of nuclear import receptors and is specific for the essential splicing factors termed SR proteins, binding specifically and directly to the arginine/serine (RS)-rich domains of these proteins.Further experiments demonstrated that this interaction occurs only when these RS domains are phosphorylated.More recently, TNPO3 was identified as an HIV dependency factor (HDF) and that depletion of TNPO3 resulted in HIV inhibition after reverse transcription but before integration, suggesting that TNPO3 may be an important drug target in HIV treatment.At least three isoforms of TNPO3 are known to exist.
Synonyms: Transportin-3, Importin-12, IPO12, TRNSR, MTR10A, TRN-SR

Pathways: Protein targeting to Nucleus