ZNF536 Antikörper (N-Term)

Produktnummer ABIN1887978

Produktdetails anti-ZNF536 Antikörper

Target: ZNF536 (Zinc Finger Protein 536 (ZNF536))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZNF536 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide from near the amino terminus of human ZNF536.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu ZNF536

Target: ZNF536 (Zinc Finger Protein 536 (ZNF536))

Andere Bezeichnung: ZNF536 (ZNF536 Produkte)

Synonyme: 9630010P11Rik antikoerper, Znf536 antikoerper, mKIAA0390 antikoerper, RGD1563363 antikoerper, zinc finger protein 536 antikoerper, ZNF536 antikoerper, Zfp536 antikoerper

Hintergrund: ZNF536 is a recently identified zinc-finger protein that is expressed primarily in the developing nervous system and the cerebral cortex, hippocampus, and hypothalamus.ZNF536 possess ten zinc fingers and interacts with CtBP1, a corepressor for gene transcription.It is most closely related to transcriptional repressor ZNF219.Overexpression of ZNF536 in embryonic stem cells dramatically reduced the mRNA levels of neuronal marker genes such as Pax6, MAP2, and beta-tubulin III following retinoic acid (RA)-induced differentiation, while depletion of ZNF536 via RNAi resulted in elevated mRNA levels of these genes, indicating its role in inhibiting neuronal cell differentiation.Overexpression of RA receptor a rescues the inhibitory role of ZNF536, suggesting that ZNF536 might inhibit RA response element-mediated transcriptional activity.
Synonyms: Zinc finger protein 536

NCBI Accession: NP_055532

Pathways: Retinoic Acid Receptor Signaling Pathway