IL-17 Antikörper (N-Term)

Produktnummer ABIN1887961

Produktdetails anti-IL-17 Antikörper

Target: IL-17 (IL17) (Interleukin 17 (IL17))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide from near the amino terminus of human IL-17A.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu IL-17

Target: IL-17 (IL17) (Interleukin 17 (IL17))

Andere Bezeichnung: IL-17 (IL17 Produkte)

Synonyme: CTLA8 antikoerper, IL-17 antikoerper, IL-17A antikoerper, IL17 antikoerper, Ctla-8 antikoerper, Ctla8 antikoerper, Il17 antikoerper, ChIL-17 antikoerper, IL-17F antikoerper, IL17A antikoerper, CTLA-8 antikoerper, interleukin 17A antikoerper, IL17A antikoerper, Il17a antikoerper

Hintergrund: Interleukin 17 (IL-17) is a family of pro-inflammatory cytokines produced by activated T cells and is thought to have a major role in the initiation and perpetuation of rheumatoid arthritis.IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases such as ERK and JNK.In addition, IL-17 stimulates the expression of IL-6 and cyclooxygenase-2 and enhances the production of nitric oxide.IL-17-producing T helper cells (TH-17 cells) have been the subject of much attention due to the importance of IL-17 in the pathogenesis of autoimmune inflammation.Because of its role in autoimmune diseases, it is thought that targeting the production and action of IL-17 would be beneficial therapeutically in these diseases.
Synonyms: Interleukin-17, IL-17A, CTLA8

NCBI Accession: NP_002181