STEAP3 Antikörper (N-Term)

Produktnummer ABIN1887914

Produktdetails anti-STEAP3 Antikörper

Target: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STEAP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität (Details): This STEAP3 antibody does not cross-react with other STEAP proteins.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide from near the amino terminus of human STEAP3.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu STEAP3

Target: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Andere Bezeichnung: STEAP3 (STEAP3 Produkte)

Synonyme: STEAP3 antikoerper, 1010001D01Rik antikoerper, Tsap6 antikoerper, pHyde antikoerper, AHMIO2 antikoerper, STMP3 antikoerper, TSAP6 antikoerper, dudlin-2 antikoerper, STEAP3 metalloreductase antikoerper, STEAP family member 3 antikoerper, STEAP3 antikoerper, steap3 antikoerper, Steap3 antikoerper

Hintergrund: The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue.Similar to two other members of the STEAP family (STEAP 2 and STEAP4), STEAP3 promotes both iron and copper reduction.STEAP3 is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome.Overexpression of STEAP3 stimulates iron reduction, mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 is an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells.
Synonyms: Six transmembrane epithelial antigen of prostate 3, dudulin-2

Pathways: Transition Metal Ion Homeostasis