FKBP15 Antikörper (N-Term)

Produktnummer ABIN1887901

Produktdetails anti-FKBP15 Antikörper

Target: FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FKBP15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide from near the amino terminus of human FKBP15.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu FKBP15

Target: FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))

Andere Bezeichnung: FKBP15 (FKBP15 Produkte)

Synonyme: KIAA0674 antikoerper, DKFZp469F024 antikoerper, BB131447 antikoerper, C430014M02Rik antikoerper, FKBO133 antikoerper, FKBP-133 antikoerper, FKBP-15 antikoerper, FKBP133 antikoerper, mKIAA0674 antikoerper, RGD1304816 antikoerper, PPP1R76 antikoerper, FK506 binding protein 15 antikoerper, si:ch211-208h16.4 antikoerper, FKBP15 antikoerper, si:ch211-208h16.4 antikoerper, Fkbp15 antikoerper

Hintergrund: FKBP15, also known as FKBP133, is a member of the FK506-binding protein family, a group of proteins initially identified as immunophilins, targets for the immunosupressant drugs FK506 and Rapamycin.FKBP15 is expressed in the developing nervous system and contains a domain similar to Wiskott-Aldrich syndrome protein homology region 1 (WH1) in addition to the FK506-binding protein motif.FKBP15 is distributed along the axonal shafts and partially co-localizes with F-actin in the growth cones of dorsal root ganglion neurons, overexpression of FKBP15 resulted in the number of filopodia in transfected neurons, suggesting that FKBP15 modulates growth cone behavior.FKBP15 has also been shown to associate with both microtubules and the actin filament systems and disruption of its expression by RNAi resulted in delayed transport of early endosomes in HeLa cells indicating that FKBP15 is also involved in the transport of early endosomes.At least three isoforms of FKBP15 are known to exist.
Synonyms: FKBP15, FK506-binding protein homolog, FKBP133, WASP and FKBP-like, WAFL

NCBI Accession: NP_056073

Pathways: SARS-CoV-2 Protein Interaktom