Cyclin O Antikörper (N-Term)

Produktnummer ABIN1887870

Produktdetails anti-Cyclin O Antikörper

Target: Cyclin O (CCNO)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin O Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide from near the amino terminus of human UNG2.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu Cyclin O

Target: Cyclin O (CCNO)

Andere Bezeichnung: Cyclin O (CCNO Produkte)

Synonyme: RGD1565217 antikoerper, ccnu antikoerper, udg2 antikoerper, ung2 antikoerper, CCNU antikoerper, MGC131111 antikoerper, C86987 antikoerper, Ccnu antikoerper, E130318K11 antikoerper, Ung2 antikoerper, UDG2 antikoerper, cyclin O antikoerper, cyclin O L homeolog antikoerper, Ccno antikoerper, ccno antikoerper, CCNO antikoerper, ccno.L antikoerper

Hintergrund: The human uracil-DNA glycosylase (UNG) gene encodes both mitochondrial (UNG1) and nuclear (UNG2) forms through differentially regulated promotes and alternative splicing.UNG2 is the major enzyme in the base excision repair pathway that removes uracil residues from DNA that arise through either misincorporation during replication or cytosine deamination.UNG2 can also be bound by the HIV-1 integrase and incorporated into the virion particle, suggesting that it is required to remove uracils from the viral genome.As the intrinsic antiviral protein APOBEC3G generates numerous uracils in the HIV genome during its replication, it may be that the UNG2 contributes to the APOBEC3G-mediated loss of infectivity by generating abasic sites in the viral genome.This UNG2 antibody will not cross-react with UNG1.
Synonyms: Uracil-DNA glycosylase 2, UDG2

NCBI Accession: NP_066970