DACT2 Antikörper (N-Term)

Produktnummer ABIN1887827

Produktdetails anti-DACT2 Antikörper

Target: DACT2 (Dapper, Antagonist of beta-Catenin 2 (DACT2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DACT2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 12 amino acid peptide from near the amino terminus of human DACT2.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu DACT2

Target: DACT2 (Dapper, Antagonist of beta-Catenin 2 (DACT2))

Andere Bezeichnung: Dact2 (DACT2 Produkte)

Synonyme: 2900084M21Rik antikoerper, A630024E20 antikoerper, Dpr2 antikoerper, Frd2 antikoerper, dapper2 antikoerper, C6orf116 antikoerper, DAPPER2 antikoerper, DPR2 antikoerper, RP11-503C24.7 antikoerper, bA503C24.7 antikoerper, dishevelled binding antagonist of beta catenin 2 antikoerper, dishevelled-binding antagonist of beta-catenin 2 antikoerper, DACT2 antikoerper, Dact2 antikoerper

Hintergrund: The Wnt signaling cascade is a conserved process in multicellular animals that plays important roles during development and can contribute to cancer and other diseases.Many members of this pathway are also expressed in the postnatal tissues such as brain.One such protein is Dact2, a member of the Dact protein family that was initially identified through binding to Disheveled (Dvl), a cytoplasmic protein essential to Wnt signaling.Dact2 is most prominent during the development of the thymus kidneys, and salivary gland.Dact2 is thought to play a role distinct from that of Dact1 with Dact2 having a greater impact on a beta-catenin-independent process termed planar cell polarity/convergent-extension signaling.Furthermore, Dact2 but not Dact1 can inhibit Nodal signaling by promoting the endocytic degradation of TGF-beta receptors.At least two isoforms of Dact2 are known to exist.
Synonyms: Dapper homolog 2, Dapper antagonist of beta-catenin 2

NCBI Accession: NP_999627