WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handhabung
Avoid freezing and thawing repeatly.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
DAPK3 antikoerper, dapk3 antikoerper, wu:fc25b08 antikoerper, si:dkey-57k2.5 antikoerper, MGC114871 antikoerper, ZIP antikoerper, ZIPK antikoerper, dlk antikoerper, Dapkl antikoerper, death associated protein kinase 3 antikoerper, death-associated protein kinase 3 antikoerper, death-associated protein kinase 3 L homeolog antikoerper, DAPK3 antikoerper, dapk3 antikoerper, dapk3.L antikoerper, Dapk3 antikoerper
Hintergrund
Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases.Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis.A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase.ZIP kinase contains an N-terminal kinase domain and a C-terminal leucine zipper structure and binds to ATF4 that is a member of ATF/CREB family.ZIP kinase has high sequence homology to DAP kinase (death-associated protein kinase), which is a mediator of apoptosis induced by gamma interferon.Overexpression of ZIP kinase induces apoptosis.ZIP and DAP kinases represent a novel kinase family, which mediates apoptosis through their catalytic activities.The messenger RNA was ubiquitously expressed in various tissues. Synonyms: ZIPK