RABGEF1 Antikörper (Center)

Produktnummer ABIN1887724

Produktdetails anti-RABGEF1 Antikörper

Target: RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))

Bindungsspezifität: Center

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RABGEF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): At least four isoforms of RABEX5 are known to exist, this antibody will recognize all four. RABEX5 antibody is predicted to not cross-react with other LRRFIP family members.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide near the center terminus of human RABEX5.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu RABGEF1

Target: RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))

Andere Bezeichnung: RABEX5 (RABGEF1 Produkte)

Synonyme: Rab5ef antikoerper, Rabex5 antikoerper, Rin2 antikoerper, RABEX5 antikoerper, rabex-5 antikoerper, rabgef1 antikoerper, RAB guanine nucleotide exchange factor (GEF) 1 antikoerper, RAB guanine nucleotide exchange factor 1 antikoerper, RAB guanine nucleotide exchange factor (GEF) 1 L homeolog antikoerper, Rabgef1 antikoerper, RABGEF1 antikoerper, rabgef1.L antikoerper

Hintergrund: RABEX5 is a guanine nucleotide exchange factor (GEF) that forms a complex with rabaptin-5 and specifically activates Rab5, a small GTPase that plays an essential role in endocytic traffic.RABEX-5 is thought to also interact with another member of the Rab family, Rab22, which targets RABEX5 to early endosomes, allowing it to activate Rab5 and thereby promote Rab5-mediated endosome fusion.
Synonyms: Rab5 GDP, GTP exchange factor, RABGEF1

NCBI Accession: NP_055319

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process