TYW3 antibody is predicted to not cross-react with other TYW protein family members. At least two isoforms of TYW3 are known to exist, this antibody will detect both isoforms.
Aufreinigung
Affinity chromatography purified via peptide column
Immunogen
17 amino acid peptide near the center of human TYW3.
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handhabung
Avoid freezing and thawing repeatly.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
Target
TYW3
(tRNA-YW Synthesizing Protein 3 Homolog (TYW3))
C1orf171 antikoerper, 5230400J09Rik antikoerper, tRNA-yW synthesizing protein 3 homolog L homeolog antikoerper, tRNA-yW synthesizing protein 3 homolog antikoerper, tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) antikoerper, tyw3.L antikoerper, TYW3 antikoerper, Tyw3 antikoerper
Hintergrund
TYW3 is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway.Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome.TYW3 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation. Synonyms: TYW3, Radical S-adenosyl methionine and flavodoxin domain-containing protein 3, tRNA wybutosine-synthesizing protein 3 homolog