ANAPC13 Antikörper (Center)

Produktnummer ABIN1887649

Produktdetails anti-ANAPC13 Antikörper

Target: ANAPC13 (Anaphase Promoting Complex Subunit 13 (ANAPC13))

Bindungsspezifität: Center

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANAPC13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the center of human APC13.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu ANAPC13

Target: ANAPC13 (Anaphase Promoting Complex Subunit 13 (ANAPC13))

Andere Bezeichnung: APC13 (ANAPC13 Produkte)

Synonyme: APC13 antikoerper, SWM1 antikoerper, 1810004D07Rik antikoerper, anaphase promoting complex subunit 13 antikoerper, ANAPC13 antikoerper, Bm1_31995 antikoerper, LOAG_01662 antikoerper, Anapc13 antikoerper

Hintergrund: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis.APC13 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence.The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex.APC13 promotes the stable association of APC3/Cdc27 and APC6/Cdc16 with the APC/C.
Synonyms: Anaphase promoting complex 13, ANAPC13, Swm1

NCBI Accession: NP_056206