KCNK18
Reaktivität: Human
WB, ELISA, IHC
Wirt: Kaninchen
Polyclonal
HRP
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handhabung
Avoid freezing and thawing repeatly.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
Target
KCNK18
(Potassium Channel Subfamily K Member 18 (KCNK18))
TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes.TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine.It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin.Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction. Synonyms: KCNK18, Potassium channel subfamily K member 18, TRIK, TRESK2