RGS21 Antikörper (Center)

Produktnummer ABIN1887624

Produktdetails anti-RGS21 Antikörper

Target: RGS21 (Regulator of G-Protein Signaling 21 (RGS21))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the center of human RGS21.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu RGS21

Target: RGS21 (Regulator of G-Protein Signaling 21 (RGS21))

Andere Bezeichnung: RGS21 (RGS21 Produkte)

Synonyme: EG624910 antikoerper, regulator of G protein signaling 21 antikoerper, regulator of G-protein signaling 21 antikoerper, regulator of G-protein signalling 21 antikoerper, RGS21 antikoerper, Rgs21 antikoerper

Hintergrund: Regulator of G-protein signaling (RGS) proteins contain an 120 amino acid conserved domain, termed the RGS domain, that acts as a GTPase-activating protein that acts to reduce the signal transmitted by the receptor-activated G-alpha subunit.RGS21 is a recently identified member of this family that has been reported to be selectively expressed in subpopulations of taste bud cells and co-expressed with bitter and sweet transduction components such as alpha-gusticin, phospholipase Cbeta2, T1R2/T1R3 sweet taste receptors and T2R bitter taste receptors.Other reports indicate that RGS21 is more widely expressed.Binding assays demonstrate that RGS21 binds alpha-gusticin in a conformation-dependent manner and may do the same with T1R receptors, suggesting that RGS21 may play a role in sweet and bitter taste transduction processes.
Synonyms: Regulator of G-protein signaling 21

NCBI Accession: NP_001034241

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling