AIFM3 Antikörper (Center)

Produktnummer ABIN1887580

Produktdetails anti-AIFM3 Antikörper

Target: AIFM3 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3))

Bindungsspezifität: Center

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AIFM3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide from near the center of human AIFM3.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu AIFM3

Target: AIFM3 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3))

Andere Bezeichnung: AIFM3 (AIFM3 Produkte)

Synonyme: nfrl-A antikoerper, MGC84340 antikoerper, AIFM3 antikoerper, LOC100150876 antikoerper, 2810401C16Rik antikoerper, AI840249 antikoerper, Aifl antikoerper, RGD1306028 antikoerper, AIFL antikoerper, apoptosis inducing factor, mitochondria associated 3 L homeolog antikoerper, apoptosis inducing factor, mitochondria associated 3 antikoerper, apoptosis-inducing factor, mitochondrion-associated 3 antikoerper, aifm3.L antikoerper, AIFM3 antikoerper, aifm3 antikoerper, Aifm3 antikoerper

Hintergrund: Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation.Recently a protein similar to the apoptosis-inducing factor (AIF) was cloned and designated AIFL (also known as AIFM3).AIFM3 is expressed ubiquitously and is predominantly localized to the inner membranes of mitochondria.Unlike AIF, AIFM3 does not translocate to the nucleus upon induction of apoptosis.However, overexpression of AIFM3, like AIF, induced cytochrome c release from the mitochondria, cleavage of caspase 3, and ultimately apoptosis, indicating AIFM3 induces apoptosis through caspase activation.Multiple isoforms of AIFM3 are known to exist.
Synonyms: Apoptosis-inducing factor mitochondrion-associated 3, AIFL

UniProt: Q96NN9

Pathways: Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis