RANBP10 Antikörper (Center)

Produktnummer ABIN1887563

Produktdetails anti-RANBP10 Antikörper

Target: RANBP10 (RAN Binding Protein 10 (RANBP10))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RANBP10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the center of human RANBP10.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu RANBP10

Target: RANBP10 (RAN Binding Protein 10 (RANBP10))

Andere Bezeichnung: RANBP10 (RANBP10 Produkte)

Synonyme: RGD1311587 antikoerper, 4432417N03Rik antikoerper, si:ch211-193l7.1 antikoerper, RAN binding protein 10 antikoerper, Ranbp10 antikoerper, RANBP10 antikoerper, ranbp10 antikoerper

Hintergrund: The RAN binding protein 10 (RANBP10) is a cytoplasmic guanine nucleotide exchange factor that shares high sequence similarity to the MET-interacting protein RANBP9.RANBP10 is expressed in the cytoplasm of mature megakaryocytes (MKs) and platelets where it localizes to polymerized noncentrosomal microtubules.RANBP10 possesses guanine nucleotide exchange factor activity towards RAN, a GTPase involved in nucleocytoplasmic traffic, spindle formation at mitosis, and nuclear envelope assembly during telophase, suggesting that RANBP10 may also be involved in these activities.RANBP10 depletion in vitro caused the disturbance of polymerized filaments in MKs and platelets in RANBP10-null mice exhibited disorders in microtubule filament numbers and localization, indicating that RANBP10 may play a significant role in maintaining microtubule dynamics.
Synonyms: RAN binding protein 10