PRICKLE2 Antikörper (Center)

Produktnummer ABIN1887562

Produktdetails anti-PRICKLE2 Antikörper

Target: PRICKLE2 (Prickle Homolog 2 (PRICKLE2))

Bindungsspezifität: Center

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRICKLE2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): Two isoforms of PRICKLE2 are known to exist. PRICKLE2 antibody is predicted to not cross-react with other PRICKLE protein family members.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the center of human PRICKLE2.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu PRICKLE2

Target: PRICKLE2 (Prickle Homolog 2 (PRICKLE2))

Andere Bezeichnung: PRICKLE2 (PRICKLE2 Produkte)

Synonyme: EPM5 antikoerper, 6230400G14Rik antikoerper, 6720451F06Rik antikoerper, mpk2 antikoerper, cb886 antikoerper, im:7138215 antikoerper, pk2 antikoerper, prickle planar cell polarity protein 2 antikoerper, prickle homolog 2b antikoerper, PRICKLE2 antikoerper, Prickle2 antikoerper, prickle2b antikoerper

Hintergrund: PRICKLE2, also known as Pk2 or EPM5, is a member of a highly conserved protein family that function in the noncanonical WNT signaling pathway which regulates intracellular calcium release and planar cell polarity.Both PRICKLE2 and the related protein PRICKLE1 are expressed in postmitotic neurons and promote neurite outgrowth , and both proteins promote neurite outgrowth via the Dishevelled dependent pathway in C1300 cells.PRICKLE2 localizes to the postsynaptic density and interacts with PSD-95 and NMDA receptors.Defects in the gene encoding PRICKLE2 are associated with autosomal recessive progressive myoclonic epilepsy.
Synonyms: REST, NRSF-interacting LIM domain protein 1, Pk2, EPM5

NCBI Accession: NP_942559