PHOX2B Antikörper (Center)

Produktnummer ABIN1887561

Produktdetails anti-PHOX2B Antikörper

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Bindungsspezifität: Center

Reaktivität: Maus, Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHOX2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): PHOX2B antibody is predicted to not cross-react with other paired homeobox family members.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the center of human PHOX2B.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu PHOX2B

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Andere Bezeichnung: PHOX2B (PHOX2B Produkte)

Synonyme: phox2 antikoerper, xphox2b antikoerper, phox2b antikoerper, PHOX2B antikoerper, pmx2b antikoerper, nbphox antikoerper, NBLST2 antikoerper, NBPhox antikoerper, PMX2B antikoerper, Dilp1 antikoerper, Pmx2b antikoerper, paired-like homeobox 2b antikoerper, paired like homeobox 2b S homeolog antikoerper, paired-like homeobox 2bb antikoerper, paired like homeobox 2b antikoerper, phox2b antikoerper, phox2b.S antikoerper, phox2bb antikoerper, PHOX2B antikoerper, Phox2b antikoerper

Hintergrund: PHOX2A and PHOX2B (Paired mesoderm homeobox protein) are closely related, paired-homeodomain transcription factors that function as determinants of the noradrenergic phenotype during embryogenesis.PHOX2 proteins are crucial for the regulation of endogenous hydroxylases in neural crest cells and promote sympathetic neuron generation.Human PHOX2B contains one DNA binding homeobox domain and is required for the differentiation of all central and nonperipheral noradrenergic centers in the brain.In contrast, PHOX2A controls only the differentiation of the main noradrenergic center of the brain.Regulation of PHOX2 may have therapeutic utility in aging or disorders involving degeneration of noradrenergic neurons .
Synonyms: Paired-like homeobox 2B, Paired mesoderm homeobox protein 2B, PMX2B, Neuroblastoma Phox, NBLST2, NBPhox

NCBI Accession: NP_003915