MEX3D Antikörper (Center)

Produktnummer ABIN1887549

Produktdetails anti-MEX3D Antikörper

Target: MEX3D (Mex-3 Homolog D (MEX3D))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MEX3D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide from near the center of human Rkhd1.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu MEX3D

Target: MEX3D (Mex-3 Homolog D (MEX3D))

Andere Bezeichnung: Rkhd1 (MEX3D Produkte)

Synonyme: RKHD1 antikoerper, MEX3D antikoerper, rkhd1 antikoerper, mex3 antikoerper, tino antikoerper, rnf193 antikoerper, ok/sw-cl.4 antikoerper, MEX-3D antikoerper, MEX3 antikoerper, OK/SW-cl.4 antikoerper, RNF193 antikoerper, TINO antikoerper, BC059858 antikoerper, Rkhd1 antikoerper, mex-3 RNA binding family member D antikoerper, mex-3 RNA binding family member D L homeolog antikoerper, mex3 RNA binding family member D antikoerper, MEX3D antikoerper, mex3d.L antikoerper, mex3d antikoerper, Mex3d antikoerper

Hintergrund: Rkhd1, also known as TINO or MEX3D is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module.MEX3 proteins, including Rkhd1, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway.These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms.Rkhd1 binds to the AU-rich element in the 3'-untranslated region of Bcl-2 mRNA and is thought to be a negative regulator of Bcl-2 expression.Rkhd3 and Rkhd4, but not Rkhd1, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.
Synonyms: RING finger and KH domain-containing protein 1, MEX3D, TINO, RING finger protein 193, RNF193

UniProt: Q86XN8