SEC62 Antikörper (C-Term)

Produktnummer ABIN1887427

Produktdetails anti-SEC62 Antikörper

Target: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SEC62 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): SEC62 antibody is predicted to not cross-react with other SEC proteins. Multiple isoforms of SEC62 are known to exist.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: SEC62 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human SEC62.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu SEC62

Target: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Andere Bezeichnung: SEC62 (TLOC1 Produkte)

Synonyme: tloc1 antikoerper, TLOC1 antikoerper, wu:fb57b06 antikoerper, zgc:114073 antikoerper, Dtrp1 antikoerper, HTP1 antikoerper, TP-1 antikoerper, 3100002M17Rik antikoerper, AI844545 antikoerper, AW545092 antikoerper, Tloc1 antikoerper, Ab2-292 antikoerper, SEC62 homolog, preprotein translocation factor S homeolog antikoerper, SEC62 homolog, preprotein translocation factor antikoerper, membrane unit of ER protein translocation apparatus antikoerper, SEC62 homolog (S. cerevisiae) antikoerper, sec62.S antikoerper, SEC62 antikoerper, sec62 antikoerper, Sec62 antikoerper

Hintergrund: SEC62 is an integral membrane protein located in the rough endoplasmic reticulum (ER) and is part of the SEC61-SEC62-SEC63 complex that is the central component of the protein translocation apparatus of the ER membrane.It is speculated that SEC61-SEC62-SEC63 may perform post-translational protein translocation into the ER and might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway.Silencing of this gene with RNAi dramatically reduced the migration and invasive potential of numerous tumor cell lines, suggesting that it may be an attractive target for therapy of various tumors.
Synonyms: Translocation protein 62, HTP1, TP-1, DTRP1, TLOC1

NCBI Accession: NP_003253