TYW1 Antikörper (C-Term)

Produktnummer ABIN1887290

Produktdetails anti-TYW1 Antikörper

Target: TYW1 (tRNA-YW Synthesizing Protein 1 Homolog (TYW1))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TYW1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): TYW1 antibody is predicted to not cross-react with other TYW protein family members. At least three isoforms of TYW1 are known to exist, this antibody will only detect the two larger isoforms.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide near the carboxy terminus of human TYW1.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu TYW1

Target: TYW1 (tRNA-YW Synthesizing Protein 1 Homolog (TYW1))

Andere Bezeichnung: TYW1 (TYW1 Produkte)

Synonyme: RSAFD1 antikoerper, TYW1A antikoerper, YPL207W antikoerper, RGD1310420 antikoerper, Rsafd1 antikoerper, AW125391 antikoerper, im:6898509 antikoerper, wu:fb74d01 antikoerper, zgc:153368 antikoerper, tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) antikoerper, S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase antikoerper, tRNA-yW synthesizing protein 1 homolog S homeolog antikoerper, tRNA-yW synthesizing protein 1 homolog antikoerper, TYW1 antikoerper, LOC100354908 antikoerper, tyw1.S antikoerper, Tyw1 antikoerper, tyw1 antikoerper

Hintergrund: TYW1, also known as TYW1A, RSAFD1 or YPL207W, is a 732 amino acid protein containing one flavodoxin-like domain that participates in the wybutosine-tRNA (Phe) biosynthesis pathway.Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome.TYW1 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation.TYW1 binds to one 4Fe-4S cluster and is located on human chromosome 7.Defects in some of the genes on chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome, suggesting that TYW1 may play a role in these conditions
Synonyms: TYW1, Radical S-adenosyl methionine and flavodoxin domain-containing protein 1, RSAFD1, tRNA wybutosine-synthesizing protein 1 homolog, TYW1A, YPL207W

NCBI Accession: NP_060734