PPPDE1 Antikörper (C-Term)

Produktnummer ABIN1887281

Produktdetails anti-PPPDE1 Antikörper

Target: PPPDE1 (PPPDE Peptidase Domain Containing 1 (PPPDE1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPPDE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide near the carboxy terminus of human PNAS4.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu PPPDE1

Target: PPPDE1 (PPPDE Peptidase Domain Containing 1 (PPPDE1))

Andere Bezeichnung: PNAS4 (PPPDE1 Produkte)

Synonyme: PPPDE1 antikoerper, FAM152A antikoerper, 5830417C01Rik antikoerper, DeSI-2 antikoerper, Fam152a antikoerper, Pppde1 antikoerper, DKFZp459O172 antikoerper, C1orf121 antikoerper, DESI antikoerper, DESI1 antikoerper, PNAS-4 antikoerper, CGI-146 antikoerper, fam152a antikoerper, pnas4 antikoerper, pppde1 antikoerper, cb238 antikoerper, desi1 antikoerper, sb:cb238 antikoerper, wu:fi12d12 antikoerper, zgc:100860 antikoerper, desumoylating isopeptidase 2 antikoerper, desumoylating isopeptidase 2 L homeolog antikoerper, DESI2 antikoerper, Desi2 antikoerper, desi2.L antikoerper, desi2 antikoerper

Hintergrund: PNAS4 is a highly conserved protein that shares high homology from plants to animals.It was initially identified as a putative apoptosis-related protein in the human acute promyelocytic leukemia cell line NB4.PNAS4 is activated during the early response to DNA damage and can inhibit proliferation via apoptosis when overexpressed in some tumor cells such as U2OS, SKOV3, and A549.PNAS4 inhibits tumor cell proliferation through the following mechanisms: (i) overexpression of PNAS4 causes S phase arrest by regulating the expression of cell cycle-related proteins and (ii) PNAS4 induces apoptosis through the mitochondrial apoptosis pathway.Recent evidence has shown that PNAS4 may be involved in the genesis of some cancers and could be a potential candidate for lung cancer therapy alone or in combination with gemcitabine.At least two isoforms of PNAS4 are known to exist.
Synonyms: PPPDE peptidase domain containing 1, CGI-146, FAM152A

NCBI Accession: NP_057160