TRIM25 Antikörper (C-Term)

Produktnummer ABIN1887269

Produktdetails anti-TRIM25 Antikörper

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM25 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide from near the carboxy terminus of human TRIM25.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu TRIM25

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Andere Bezeichnung: TRIM25 (TRIM25 Produkte)

Synonyme: zgc:55773 antikoerper, MGC130751 antikoerper, EFP antikoerper, RNF147 antikoerper, Z147 antikoerper, ZNF147 antikoerper, AA960166 antikoerper, AL022677 antikoerper, Zfp147 antikoerper, Efp antikoerper, Znf147 antikoerper, E3 ubiquitin/ISG15 ligase TRIM25 antikoerper, tripartite motif containing 25 antikoerper, E3 ubiquitin/ISG15 ligase TRIM25-like L homeolog antikoerper, microRNA 3614 antikoerper, tripartite motif-containing 25 antikoerper, LOC100146440 antikoerper, trim25 antikoerper, LOC100490741.L antikoerper, TRIM25 antikoerper, MIR3614 antikoerper, Trim25 antikoerper

Hintergrund: TRIM25, also known as estrogen responsive finger protein (EFP) is a member of the RING finger-B box-coiled coil family and is a downstream target of estrogen receptor a.Mice lacking this gene displayed an underdeveloped uterus and reduced estrogen responsiveness demonstrating that this protein is essential for estrogen dependent proliferation.TRIM25 expression is increased in breast carcinoma where it promotes the growth of breast tumor by functioning as an E3 ubiquitin ligase that targets the negative cell cycle checkpoint 14-3-3s.Recent reports have indicated that TRIM25 E3 ubiquitin ligase is essential for the retinoic-acid-inducible gene 1 (RIG-1) signaling pathway to elicit host antiviral innate immunity.
Synonyms: Tripartite motif-containing 25, estrogen responsive finger protein, EFP

NCBI Accession: NP_005073