ESRP2 Antikörper (C-Term)

Produktnummer ABIN1887203

Produktdetails anti-ESRP2 Antikörper

Target: ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ESRP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): RBM35B antibody is predicted to not cross-react with other RBM35/ESRP family members. At least three isoforms of RBM35B are known to exist, this antibody will detect all three.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the carboxy terminus of human RBM35B.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu ESRP2

Target: ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

Andere Bezeichnung: RBM35B (ESRP2 Produkte)

Synonyme: RBM35B antikoerper, 9530027K23Rik antikoerper, Rbm35b antikoerper, RGD1310855 antikoerper, cb404 antikoerper, fa07a06 antikoerper, rbm35b antikoerper, sb:cb404 antikoerper, zgc:77254 antikoerper, epithelial splicing regulatory protein 2 antikoerper, microRNA 6773 antikoerper, ESRP2 antikoerper, Esrp2 antikoerper, MIR6773 antikoerper, esrp2 antikoerper

Hintergrund: RBM35A, also known as ESRP2, is a mRNA splicing factor that with its related protein RBM35A (ESRP1) are coordinators of an epithelial cell-type-specific splicing program.Both RBM35B and RBM35A are involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs, suggesting that these proteins are global regulators of an epithelial regulatory network.Loss of this global ESRP-regulated epithelial splicing programme induces the phenotypic changes in cell morphology that are observed during the epithelial-mesenchymal transition.
Synonyms: RNA-binding motif protein 35B, RMB35B, Epithelial splicing regulatory protein 2, ESRP2

NCBI Accession: NP_079215