TRIM30 Antikörper (C-Term)

Produktnummer ABIN1887160

Produktdetails anti-TRIM30 Antikörper

Target: TRIM30 (Trim30) (Tripartite Motif Containing 30 (Trim30))

Bindungsspezifität: C-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM30 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the carboxy terminus of the mouse TRIM30.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu TRIM30

Target: TRIM30 (Trim30) (Tripartite Motif Containing 30 (Trim30))

Andere Bezeichnung: TRIM30 (Trim30 Produkte)

Synonyme: RGD1563970 antikoerper, Rpt-1 antikoerper, Rpt1 antikoerper, Trim30 antikoerper, tripartite motif-containing 30 antikoerper, tripartite motif-containing 30A antikoerper, Trim30 antikoerper, Trim30a antikoerper

Hintergrund: TRIM30 belongs to a family of the tripartite motif (TRIM) proteins involved in the regulation of cell proliferation, differentiation, development, oncogenesis, apoptosis and antiviral responses.The TRIM protein family is an expanding family of RING ('really interesting new gene') proteins, also known as RBCC proteins as they contain an RBCC motif, which comprises a RING domain, one or two B-boxes and a predicted coiled-coil region.Studies have shown that some TRIM family members are critical to innate immunity, TRIM5, TRIM19 and TRIM25, for example, have been shown to restrict viral infection.A recent study shows that TRIM30 functions as a negative modulator of the TLR signaling pathway, by targeting TAB2 and TAB3, and contributes to the inhibition of TLR-mediated NF-kappaB activation.The importance of TRIM30 in the attenuation or termination of NF-kappaB activation suggests that targeting of TAB2 and TAB3 by TRIM30alpha may be a mechanism for modulating many types of immune responses.
Synonyms: Tripartite motif-containing 30, Rpt-1, Rpt1, down regulatory protein of interleukin 2 receptor

NCBI Accession: NP_033125