HILPDA Antikörper (C-Term)

Produktnummer ABIN1887137

Produktdetails anti-HILPDA Antikörper

Target: HILPDA (Hypoxia Inducible Lipid Droplet-Associated (HILPDA))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HILPDA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): At least two isoforms of HIG2 are known to exist, this antibody will detect both isoforms. HIG2 antibody is predicted to not cross-react with HIG1

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the carboxy terminus of human HIG2.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu HILPDA

Target: HILPDA (Hypoxia Inducible Lipid Droplet-Associated (HILPDA))

Andere Bezeichnung: HIG2 (HILPDA Produkte)

Synonyme: 2310016C08Rik antikoerper, AW049004 antikoerper, Hig2 antikoerper, C7orf68 antikoerper, HIG-2 antikoerper, HIG2 antikoerper, hypoxia inducible lipid droplet associated antikoerper, Hilpda antikoerper, HILPDA antikoerper

Hintergrund: HIG1 and HIG2 (Hypoxia-inducible gene 1 and 2, respectively) are known to be induced by hypoxic conditions.HIG2 is induced by hypoxia and by glucose deprivation in cultured cells.In addition, tumor xenografts derived from human cervical cancer cells display increased expression of HIG1 and HIG2 when they are deprived of oxygen.Unlike HIG2, which is ubiquitously expressed and might be an activator and target of the canonical Wnt pathway, the function and the mechanisms underlying its regulation of HIG1 still remained unknown.The putative link between hypoxia and an oncogenic signaling pathway might play an important role in tumorigenesis.
Synonyms: Hypoxia-inducible gene 2 protein, HIG-2

NCBI Accession: NP_001092256