FNIP2 Antikörper (C-Term)

Produktnummer ABIN1887136

Produktdetails anti-FNIP2 Antikörper

Target: FNIP2 (Folliculin Interacting Protein 2 (FNIP2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FNIP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität (Details): Multiple isoforms of FNIP2 are known to exist. This antibody is predicted to not cross-react with FNIP1.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the carboxy terminus of human FNIP2.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu FNIP2

Target: FNIP2 (Folliculin Interacting Protein 2 (FNIP2))

Andere Bezeichnung: FNIP2 (FNIP2 Produkte)

Synonyme: LOC797213 antikoerper, FNIPL antikoerper, MAPO1 antikoerper, D630023B12Rik antikoerper, mKIAA1450 antikoerper, RGD1562174 antikoerper, folliculin interacting protein 2 antikoerper, si:ch211-42i9.8 antikoerper, FNIP2 antikoerper, si:ch211-42i9.8 antikoerper, fnip2 antikoerper, Fnip2 antikoerper

Hintergrund: FNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene.Folliculin is thought to act as a tumor suppressor as mutations or loss of heterozygosity in this gene are associated with BHD syndrome-related renal tumors.Folliculin and FNIP1, a protein that shares 49% identity to FNIP2, bind to AMPK, an important energy sensor in cells that negatively regulates the mammalian target of rapamycin (mTOR), a protein that is thought to be the master switch for cell growth and proliferation.FNIP1 and FNIP2 are able to form homo- and heteromeric multimers, suggesting these proteins may have a functional relationship.
Synonyms: Folliculin interacting protein 2, FNIPL

NCBI Accession: NP_065891