SLITRK1 Antikörper (C-Term)

Produktnummer ABIN1887118

Produktdetails anti-SLITRK1 Antikörper

Target: SLITRK1 (SLIT and NTRK-Like Family, Member 1 (SLITRK1))

Bindungsspezifität: C-Term

Reaktivität: Ratte, Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLITRK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität (Details): This antibody is predicted to have no cross-reactivity to other Slitrk proteins.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide from near the carboxy terminus of human Slitrk1.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu SLITRK1

Target: SLITRK1 (SLIT and NTRK-Like Family, Member 1 (SLITRK1))

Andere Bezeichnung: Slitrk1 (SLITRK1 Produkte)

Synonyme: DKFZp459G0529 antikoerper, LRRC12 antikoerper, TTM antikoerper, 3200001I04Rik antikoerper, SLIT and NTRK like family member 1 antikoerper, SLIT and NTRK-like family, member 1 antikoerper, SLITRK1 antikoerper, slitrk1 antikoerper, Slitrk1 antikoerper

Hintergrund: SLIT and NTRK-like family 1 (Slitrk1) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein.These proteins are also homologous to trk neurotrophin receptors in their intracellular domains.Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family.For example, Slitrk1 is expressed primarily in mature neurons.Overexpression of Slitrk1 in transfected neuronal cells induced unipolar neurites, while expression of the other Slitrk proteins inhibited neurite outgrowth, suggesting that these proteins are involved in the control of neurite outgrowth.While Slitrk1 variants have been suggested associated with Tourette's Syndrome, it is thought to play only a minor role if at all.
Synonyms: SLIT and NTRK-like family 1

NCBI Accession: NP_443142