SYPL2 Antikörper (C-Term)

Produktnummer ABIN1887064

Produktdetails anti-SYPL2 Antikörper

Target: SYPL2 (Synaptophysin-Like 2 (SYPL2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYPL2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Kreuzreaktivität (Details): At least two isoforms of SYPL2 are known to exist. SYPL2 antibody will not cross-react with SYPL1.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the carboxy terminus of human SYPL.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu SYPL2

Target: SYPL2 (Synaptophysin-Like 2 (SYPL2))

Andere Bezeichnung: SYPL2 (SYPL2 Produkte)

Synonyme: AI552439 antikoerper, Mg29 antikoerper, MG29 antikoerper, mg29 antikoerper, MGC88982 antikoerper, Sypl antikoerper, fc22a07 antikoerper, wu:fc22a07 antikoerper, zgc:110355 antikoerper, sypl antikoerper, wu:fd54d09 antikoerper, zgc:65838 antikoerper, synaptophysin-like 2 antikoerper, synaptophysin like 2 antikoerper, synaptophysin like 2 S homeolog antikoerper, synaptophysin-like 2b antikoerper, synaptophysin-like 2a antikoerper, Sypl2 antikoerper, SYPL2 antikoerper, sypl2.S antikoerper, sypl2 antikoerper, sypl2b antikoerper, sypl2a antikoerper

Hintergrund: SYPL2, also known as Mitsugumin 29, was initially identified as a transmembrane protein from the triad junction in skeletal muscle that had significant homology with members of the synaptophysin family.SYPL2 is thought to participate in the excitation-contraction coupling process of skeletal muscle as SYPL2-null mice showed reduced muscle contractile force and altered triad junction structure and increased susceptibility to fatigue of the skeletal muscle.SYPL2 plays a critical role in muscle Ca2+ signaling by regulating the process of store-operated Ca2+ entry and interacts with ryanodine receptor (RyR), thereby influencing intracellular Ca2+ homeostasis through changes in the RyR/Ca2+ release function.Co-expression of SYPL2 and RyR in cultured cells leads to apoptotic cell death resulting from the depletion of Ca2+ from the intracellular stores.
Synonyms: SYPL2, Synaptophysin-like protein 2, mitsugumin 29, MG29

NCBI Accession: NP_001035799