BICD1 Antikörper (C-Term)

Produktnummer ABIN1887005

Produktdetails anti-BICD1 Antikörper

Target: BICD1 (Bicaudal D Homolog 1 (BICD1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BICD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Spezifität: At least two isoforms of BICD1 are known to exist, this antibody will only recognize the larger isoform.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide from near the carboxy terminus of human BICD1.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu BICD1

Target: BICD1 (Bicaudal D Homolog 1 (BICD1))

Andere Bezeichnung: BICD1 (BICD1 Produkte)

Synonyme: BICD antikoerper, B830009D06Rik antikoerper, mKIAA4125 antikoerper, bicaudal D homolog 1 L homeolog antikoerper, BICD cargo adaptor 1 antikoerper, bicaudal D homolog 1 (Drosophila) antikoerper, bicd1.L antikoerper, BICD1 antikoerper, Bicd1 antikoerper

Hintergrund: BICD1 was initially identified as the human homolog to Drosophila Bicaudal-D protein that forms part of the cytoskeleton and mediates the correct sorting of mRNAs for oocyte- and axis-determining factors during oogenesis.BICD1 can bind to dynein-dynactin and co-localizes with Rab6A on the trans-Golgi network and cytoplasmic vesicles, suggesting BICD1 regulates COPI-independent Golgi-ER transport.BICD1 will also interact with Rab6B, a Rab6 isoform that is expressed primarily in brain.Live cell imaging showed bi-directional movement of Rab6B structures in SK-N-SH neurites, indicating that BICD1 is involved in the Rab6B regulation of retrograde cargo transport in neuronal cells.
Synonyms: Bicaudal D homolog 1

NCBI Accession: NP_001705

Pathways: Ribonucleoprotein Complex Subunit Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, Maintenance of Protein Location