PPAPDC2
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
FITC
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handhabung
Avoid freezing and thawing repeatly.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
Target
PPAPDC2
(Phosphatidic Acid Phosphatase Type 2 Domain Containing 2 (PPAPDC2))
PPAPDC2 is a phosphatase that dephosphorylates Presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may have important role in innate immunity.PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation.PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid.PPAPDC2 activity is independent of Mg2+ and has been identified in activated human neutrophil (PMN) extracts.It is widely expressed in human tissues.Recent studies shows PPAPDC2 is a functional isoprenoid diphosphate phosphatase. Synonyms: Phosphatidic acid phosphatase type 2 domain containing 2, PSD