RPA 14 kDa Subunit (AA 1-91) Antikörper

Produktnummer ABIN1885936

Produktdetails

Target: RPA 14 kDa Subunit

Bindungsspezifität: AA 1-91

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 91 of RPA 14 kDa subunit

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 1 x PBS, 1 % BSA, 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Antigendetails

Target: RPA 14 kDa Subunit

Hintergrund: Required for DNA recombination, repair and replication.The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.Functions as component of the alternative replication protein A complex (aRPA).aRPA binds single-stranded DNA and probably plays a role in DNA repair, it does not support chromosomal DNA replication and cell cycle progression through S-phase.In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.

Gen-ID: 6119

NCBI Accession: NM_002947, NP_002938