SUMO2/3 Antikörper (C-Term)

Produktnummer ABIN1882138

Produktdetails anti-SUMO2/3 Antikörper

Target: SUMO2/3 (Small Ubiquitin Related Modifier 2/3 (SUMO2/3))

Bindungsspezifität: AA 53-84, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUMO2/3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: X, Zf, B, C, Ha, Pr, M, Pig, Rat

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This SUMO2/3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-84 amino acids from the C-terminal region of human SUMO2/3.

Klon: RB15398

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-SUMO2/3 Antikörper (ABIN1882138)

Oh, Claussen, Kim: "Motor and sensory demyelinating mononeuropathy multiplex (multifocal motor and sensory demyelinating neuropathy): a separate entity or a variant of chronic inflammatory demyelinating polyneuropathy?" in: Journal of the peripheral nervous system : JPNS, Vol. 2, Issue 4, pp. 362-9, (2000) (PubMed).

Mannen, Tseng, Cho, Li: "Cloning and expression of human homolog HSMT3 to yeast SMT3 suppressor of MIF2 mutations in a centromere protein gene." in: Biochemical and biophysical research communications, Vol. 222, Issue 1, pp. 178-80, (1996) (PubMed).

Details zu SUMO2/3

Target: SUMO2/3 (Small Ubiquitin Related Modifier 2/3 (SUMO2/3))

Andere Bezeichnung: SUMO2/3 (SUMO2/3 Produkte)

Synonyme: SUMO2 antikoerper, small ubiquitin-like modifier 2 antikoerper, SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)-like antikoerper, small ubiquitin-related modifier 2 antikoerper, SUMO2 antikoerper, LOC711990 antikoerper, LOC714892 antikoerper

Hintergrund: SUMO2 and SUMO3 are members of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.

Molekulargewicht: 11637

NCBI Accession: NP_008867

UniProt: P55854