TAF11 Antikörper (N-Term)

Produktnummer ABIN1881867

Produktdetails anti-TAF11 Antikörper

Target: TAF11 (TATA Box Binding Protein Associated Factor 11 (TAF11))

Bindungsspezifität: AA 1-30, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TAF11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TAF11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TAF11.

Klon: RB41941

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-TAF11 Antikörper (ABIN1881867)

Matsuoka, Ballif, Smogorzewska, McDonald, Hurov, Luo, Bakalarski, Zhao, Solimini, Lerenthal, Shiloh, Gygi, Elledge: "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, (2007) (PubMed).

Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, (2003) (PubMed).

Guermah, Ge, Chiang, Roeder: "The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis." in: Molecular cell, Vol. 12, Issue 4, pp. 991-1001, (2003) (PubMed).

Mengus, Gangloff, Carré, Lavigne, Davidson: "The human transcription factor IID subunit human TATA-binding protein-associated factor 28 interacts in a ligand-reversible manner with the vitamin D(3) and thyroid hormone receptors." in: The Journal of biological chemistry, Vol. 275, Issue 14, pp. 10064-71, (2000) (PubMed).

Birck, Poch, Romier, Ruff, Mengus, Lavigne, Davidson, Moras: "Human TAF(II)28 and TAF(II)18 interact through a histone fold encoded by atypical evolutionary conserved motifs also found in the SPT3 family." in: Cell, Vol. 94, Issue 2, pp. 239-49, (1998) (PubMed).

Details zu TAF11

Target: TAF11 (TATA Box Binding Protein Associated Factor 11 (TAF11))

Andere Bezeichnung: TAF11 (TAF11 Produkte)

Synonyme: 1110038O14Rik antikoerper, 28kDa antikoerper, AI115401 antikoerper, AL024207 antikoerper, AW552398 antikoerper, PRO214 antikoerper, TAF2I antikoerper, TAFII28 antikoerper, MGC:15243 antikoerper, TATA-box binding protein associated factor 11 antikoerper, Taf11 antikoerper, TAF11 antikoerper

Hintergrund: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure.

Molekulargewicht: 23307

NCBI Accession: NP_001257417, NP_005634

UniProt: Q15544