POLR2G Antikörper (C-Term)

Produktnummer ABIN1881671

Produktdetails anti-POLR2G Antikörper

Target: POLR2G (Polymerase (RNA) II (DNA Directed) Polypeptide G (POLR2G))

Bindungsspezifität: AA 125-154, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLR2G Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: B, Zf, M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This POLR2G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-154 amino acids from the C-terminal region of human POLR2G.

Klon: RB42404

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-POLR2G Antikörper (ABIN1881671)

Cojocaru, Jeronimo, Forget, Bouchard, Bergeron, Côte, Poirier, Greenblatt, Coulombe: "Genomic location of the human RNA polymerase II general machinery: evidence for a role of TFIIF and Rpb7 at both early and late stages of transcription." in: The Biochemical journal, Vol. 409, Issue 1, pp. 139-47, (2007) (PubMed).

Ujvári, Luse: "RNA emerging from the active site of RNA polymerase II interacts with the Rpb7 subunit." in: Nature structural & molecular biology, Vol. 13, Issue 1, pp. 49-54, (2006) (PubMed).

Meka, Werner, Cordell, Onesti, Brick: "Crystal structure and RNA binding of the Rpb4/Rpb7 subunits of human RNA polymerase II." in: Nucleic acids research, Vol. 33, Issue 19, pp. 6435-44, (2005) (PubMed).

Zhou, Deng, Kashanchi, Brady, Shatkin, Kumar: "The Tat/TAR-dependent phosphorylation of RNA polymerase II C-terminal domain stimulates cotranscriptional capping of HIV-1 mRNA." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 22, pp. 12666-71, (2003) (PubMed).

Details zu POLR2G

Target: POLR2G (Polymerase (RNA) II (DNA Directed) Polypeptide G (POLR2G))

Andere Bezeichnung: POLR2G (POLR2G Produkte)

Synonyme: RPB19 antikoerper, RPB7 antikoerper, hRPB19 antikoerper, hsRPB7 antikoerper, Rpb7 antikoerper, POLR2G antikoerper, 2410046K11Rik antikoerper, A230108L04Rik antikoerper, C76415 antikoerper, RBP7 antikoerper, Rpo2-7l antikoerper, RNA polymerase II subunit G antikoerper, polymerase (RNA) II (DNA directed) polypeptide G antikoerper, polymerase (RNA) II (DNA directed) polypeptide G L homeolog antikoerper, POLR2G antikoerper, Polr2g antikoerper, polr2g antikoerper, polr2g.L antikoerper

Hintergrund: This gene encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The protein functions in transcription initiation, and is also thought to help stabilize transcribing polyermase molecules during elongation.

Molekulargewicht: 19294

NCBI Accession: NP_002687

UniProt: P62487

Pathways: Regulatorische RNA Pathways