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HIST2H2BE Antikörper (N-Term)
HIST2H2BE
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
RB41930
unconjugated
Produktnummer ABIN1881418
Produktdetails anti-HIST2H2BE Antikörper
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Target
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HIST2H2BE
(Histone H2B Type 2-E (HIST2H2BE))
Bindungsspezifität
Alle Epitope für HIST2H2BE Antikörper
AA 12-40, N-Term
Reaktivität
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Human
Wirt
Alle Wirte für HIST2H2BE Antikörper
Kaninchen
Klonalität
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Polyklonal
Konjugat
Alle Konjugate für HIST2H2BE Antikörper
Dieser HIST2H2BE Antikörper ist unkonjugiert
Applikation
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Western Blotting (WB)
Homologie
M
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This HIST2H2BE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human HIST2H2BE.
Klon
RB41930
Isotyp
Ig Fraction
Top Product
Discover our top product HIST2H2BE Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Referenzen für anti-HIST2H2BE Antikörper (ABIN1881418)
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Kim, Guermah, McGinty, Lee, Tang, Milne, Shilatifard, Muir, Roeder : "RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells. " in: Cell , Vol. 137 , Issue 3 , pp. 459-71 , (2009 ) (PubMed ).
Pankratova, Manuĭlova, Stepchenko : "[Role of transcription factors binding sites in no-mediated histone H2B promoter repression]. " in: Molekuliarnaia biologiia , Vol. 43 , Issue 2 , pp. 368-73 , (2009 ) (PubMed ).
Dai, Yu, Goh, Chng, Tan, Fu, Zheng, Luo : "Histone 2B (H2B) expression is confined to a proper NAD+/NADH redox status. " in: The Journal of biological chemistry , Vol. 283 , Issue 40 , pp. 26894-901 , (2008 ) (PubMed ).
Zhao, Lang, Ito, Bonnet, Metzger, Sawatsubashi, Suzuki, Le Guezennec, Stunnenberg, Krasnov, Georgieva, Schüle, Takeyama, Kato, Tora, Devys : "A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing. " in: Molecular cell , Vol. 29 , Issue 1 , pp. 92-101 , (2008 ) (PubMed ).
Kawasaki, Schiltz, Chiu, Itakura, Taira, Nakatani, Yokoyama : "ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation. " in: Nature , Vol. 405 , Issue 6783 , pp. 195-200 , (2000 ) (PubMed ).
Details zu HIST2H2BE
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Target
HIST2H2BE
(Histone H2B Type 2-E (HIST2H2BE))
Andere Bezeichnung
HIST2H2BE (HIST2H2BE Produkte )
Synonyme
RGD1562346 antikoerper, AV127319 antikoerper, H2b-613 antikoerper, T25626 antikoerper, DKFZp469C0528 antikoerper, H2b antikoerper, GL105 antikoerper, H2B antikoerper, H2B.1 antikoerper, H2BFQ antikoerper, H2BGL105 antikoerper, H2BQ antikoerper, histone cluster 2 H2B family member E antikoerper, histone cluster 2, H2be antikoerper, histone cluster 1, H2bl antikoerper, histone cluster 2 H2B family member e antikoerper, histone H2B antikoerper, Hist2h2be antikoerper, HIST2H2BE antikoerper, Hist1h2bl antikoerper, H2B antikoerper
Hintergrund
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
Molekulargewicht
13920
NCBI Accession
NP_003519
UniProt
Q16778
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