DNAI2 Antikörper (C-Term)

Produktnummer ABIN1881264

Produktdetails anti-DNAI2 Antikörper

Target: DNAI2 (Dynein, Axonemal, Intermediate Chain 2 (DNAI2))

Bindungsspezifität: AA 484-513, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNAI2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DNAI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 484-513 amino acids from the C-terminal region of human DNAI2.

Klon: RB41653

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-DNAI2 Antikörper (ABIN1881264)

Loges, Olbrich, Fenske, Mussaffi, Horvath, Fliegauf, Kuhl, Baktai, Peterffy, Chodhari, Chung, Rutman, OCallaghan, Blau, Tiszlavicz, Voelkel, Witt, Zietkiewicz, Neesen, Reinhardt, Mitchison, Omran: "DNAI2 mutations cause primary ciliary dyskinesia with defects in the outer dynein arm." in: American journal of human genetics, Vol. 83, Issue 5, pp. 547-58, (2008) (PubMed).

Pennarun, Chapelin, Escudier, Bridoux, Dastot, Cacheux, Goossens, Amselem, Duriez: "The human dynein intermediate chain 2 gene (DNAI2): cloning, mapping, expression pattern, and evaluation as a candidate for primary ciliary dyskinesia." in: Human genetics, Vol. 107, Issue 6, pp. 642-9, (2001) (PubMed).

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).

Details zu DNAI2

Target: DNAI2 (Dynein, Axonemal, Intermediate Chain 2 (DNAI2))

Andere Bezeichnung: DNAI2 (DNAI2 Produkte)

Synonyme: MGC115449 antikoerper, CILD9 antikoerper, DIC2 antikoerper, C030015H18Rik antikoerper, Dnai2 antikoerper, Gm728 antikoerper, Dnaic2 antikoerper, dynein axonemal intermediate chain 2 antikoerper, dynein axonemal intermediate chain 2 S homeolog antikoerper, dynein, axonemal, intermediate chain 2 antikoerper, DNAI2 antikoerper, dnai2.S antikoerper, dnai2 antikoerper, Dnaic2 antikoerper, Dnai2 antikoerper

Hintergrund: The protein encoded by this gene belongs to the dynein intermediate chain family, and is part of the dynein complex of respiratory cilia and sperm flagella. Mutations in this gene are associated with primary ciliary dyskinesia type 9. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Molekulargewicht: 68821

NCBI Accession: NP_001166281, NP_075462

UniProt: Q9GZS0