ATP8B3 Antikörper (N-Term)

Produktnummer ABIN1881094

Produktdetails anti-ATP8B3 Antikörper

Target: ATP8B3 (ATPase, Aminophospholipid Transporter, Class I, Type 8B, Member 3 (ATP8B3))

Bindungsspezifität: AA 56-84, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP8B3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ATP8B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-84 amino acids from the N-terminal region of human ATP8B3.

Klon: RB42178

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-ATP8B3 Antikörper (ABIN1881094)

Scott, Muglia, Kong, Guan, Flickinger, Upmanyu, Tozzi, Li, Burmeister, Absher, Thompson, Francks, Meng, Antoniades, Southwick, Schatzberg, Bunney, Barchas, Jones, Day, Matthews, McGuffin et al.: "Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry...." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 18, pp. 7501-6, (2009) (PubMed).

Harris, Arias: "FIC1, a P-type ATPase linked to cholestatic liver disease, has homologues (ATP8B2 and ATP8B3) expressed throughout the body." in: Biochimica et biophysica acta, Vol. 1633, Issue 2, pp. 127-31, (2003) (PubMed).

Halleck, Lawler JF, Blackshaw, Gao, Nagarajan, Hacker, Pyle, Newman, Nakanishi, Ando, Weinstock, Williamson, Schlegel: "Differential expression of putative transbilayer amphipath transporters." in: Physiological genomics, Vol. 1, Issue 3, pp. 139-50, (2000) (PubMed).

Fries, Svendsen: "Studies on Tyzzer's disease in rats." in: Laboratory animals, Vol. 12, Issue 1, pp. 1-4, (1978) (PubMed).

Details zu ATP8B3

Target: ATP8B3 (ATPase, Aminophospholipid Transporter, Class I, Type 8B, Member 3 (ATP8B3))

Andere Bezeichnung: ATP8B3 (ATP8B3 Produkte)

Synonyme: ATPIK antikoerper, ATPase phospholipid transporting 8B3 antikoerper, ATP8B3 antikoerper

Hintergrund: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. This gene encodes the member 3 of the phospholipid-transporting ATPase 8B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Molekulargewicht: 146752

NCBI Accession: NP_001171473, NP_620168

UniProt: O60423