Acetylcholinesterase Antikörper

Produktnummer ABIN1870760

Produktdetails anti-Acetylcholinesterase Antikörper

Target: Acetylcholinesterase (AChE)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Acetylcholinesterase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide of human ACHE

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:200 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
FC 1:20 - 1:50

Kommentare:

Isoform H is highly expressed in erythrocytes

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu Acetylcholinesterase

Target: Acetylcholinesterase (AChE)

Andere Bezeichnung: ACHE (AChE Produkte)

Synonyme: ACEE antikoerper, ARACHE antikoerper, N-ACHE antikoerper, YT antikoerper, Ache antikoerper, GB14873 antikoerper, zgc:92550 antikoerper, ACE antikoerper, Dsim\\GD20515 antikoerper, GD20515 antikoerper, dsim_GLEANR_4292 antikoerper, ache antikoerper, mE1a antikoerper, mE1b antikoerper, mE1c antikoerper, mE1c-long antikoerper, mE1d antikoerper, mE1d' antikoerper, mE1e antikoerper, arache antikoerper, n-ache antikoerper, acetylcholinesterase (Cartwright blood group) antikoerper, acetylcholinesterase 2 antikoerper, acetylcholinesterase antikoerper, Acetylcholine esterase antikoerper, acetylcholinesterase (Cartwright blood group) L homeolog antikoerper, collagen type I alpha 2 chain antikoerper, ACHE antikoerper, AChE-2 antikoerper, Ache antikoerper, ache antikoerper, Dsim\Ace antikoerper, ache.L antikoerper, COL1A2 antikoerper, ACE-1 antikoerper

Hintergrund: Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally.

Molekulargewicht: 67.796 kDa

Gen-ID: 43

UniProt: P22303

Pathways: Skeletal Muscle Fiber Development