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CD33 Antikörper (AA 15-237)

CD33 Reaktivität: Human FACS, WB, ELISA, IHC Wirt: Maus Monoclonal unconjugated
Produktnummer ABIN1845398
  • Target Alle CD33 Antikörper anzeigen
    CD33
    Bindungsspezifität
    • 16
    • 16
    • 13
    • 9
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 15-237
    Reaktivität
    • 165
    • 35
    • 15
    • 13
    • 7
    • 6
    • 3
    • 1
    Human
    Wirt
    • 92
    • 79
    Maus
    Klonalität
    • 89
    • 81
    • 1
    Monoklonal
    Konjugat
    • 56
    • 16
    • 13
    • 12
    • 10
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD33 Antikörper ist unkonjugiert
    Applikation
    • 107
    • 99
    • 40
    • 30
    • 26
    • 26
    • 22
    • 22
    • 16
    • 13
    • 9
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human CD33 (AA: 15-237) expressed in E. coli.
    Isotyp
    IgG1
    Top Product
    Discover our top product CD33 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.0 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
  • Target
    CD33
    Andere Bezeichnung
    CD33 (CD33 Produkte)
    Synonyme
    SIGLEC-3 antikoerper, SIGLEC3 antikoerper, p67 antikoerper, Siglec-3 antikoerper, gp67 antikoerper, CD33 molecule antikoerper, CD33 antigen antikoerper, CD33 antikoerper, Cd33 antikoerper
    Hintergrund
    The protein encoded by this gene belongs to putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells.Preferentially binds to alpha-2,6-linked sialic acid.The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase (s) via their SH2 domain (s) that block signal transduction through dephosphorylation of signaling molecules.Induces apoptosis in acute myeloid leukemia (in vitro) and CD33 plays potential key roles in the pathogenesis of Alzheimer's disease (AD).
    Molekulargewicht
    39.8 kDa
    Gen-ID
    945
    UniProt
    P20138
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