MTOR Antikörper (Ser2448)
Kurzübersicht für MTOR Antikörper (Ser2448) (ABIN1822694)
Target
Alle MTOR (mTOR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Ser2448
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Spezifität
- Endogenous levels of human mTOR only when phosphorylated at Ser2448. Species Crossreactivity: mouse, rat.
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Aufreinigung
- Purified
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Immunogen
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Synthetic peptide corresponding to residues surrounding Ser2448 of human mTOR.
Type of Immunogen: Synthetic peptide -
Isotyp
- IgG
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Applikationshinweise
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Approved: IF (1:50), IP (1:50), WB
Usage: Western Blot: 1:1000 Incubate membrane with diluted antibody in 5 % BSA, 1X TBS, 0.1 % Tween-20 at 4 °C with gentle shaking, overnight. -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, 100 μg/mL BSA, less than 0.02 % sodium azide, 50 % glycerol
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Aliquot to avoid repeated freezing and thawing.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.
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- MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))
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Andere Bezeichnung
- MTOR
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Hintergrund
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Name/Gene ID: MTOR
Subfamily: PI3/PI4
Family: Protein Kinase
Synonyms: MTOR, FRAP1, FRAP2, FRAP, Mammalian target of rapamycin, RAFT1, Rapamycin and FKBP12 target 1, RAPT1, Rapamycin target protein 1 -
Gen-ID
- 2475
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UniProt
- P42345
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Pathways
- PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagie, CXCR4-mediated Signaling Events, BCR Signaling, Warburg Effekt
Target
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