MMP1 Antikörper (C-Term)
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- Target Alle MMP1 Antikörper anzeigen
- MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser MMP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- Recognizes human matrix metalloproteinase 1 (MMP-1). The MMPs are zinc-dependent endopeptidases responsible for degrading the extracellular matrix. They are also involved in cell proliferation, migration, differentiation and apoptosis. Most MMPs are synthesized as inactive zymogens and a propeptide region must be cleaved off before the enzyme becomes active. Their expression is increased dramatically in a variety of cancer types, where it indicates invasive disease and a poor prognosis. MMP-1 is one of the collagenases, capable of degrading collagens I, II and III, all main components of the interstitial stroma. It is overexpressed in invasive melanoma, colorectal and esophageal cancers. It has also been implicated in arthritis and might influence atherosclerotic lesion formation. It might also be involved in the repair processes of the heart after myocardial infarction.
- Aufreinigung
- Protein G purified
- Immunogen
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Ovalbumin conjugated synthetic peptide corresponding to a region within the C-terminus of human MMP-1.
Type of Immunogen: Synthetic peptide - Klon
- 3B6
- Isotyp
- IgG1
- Top Product
- Discover our top product MMP1 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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Target Species of Antibody: Human
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- PBS, 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Target
- MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
- Andere Bezeichnung
- MMP1 (MMP1 Produkte)
- Synonyme
- CLG antikoerper, CLGN antikoerper, Mmp1a antikoerper, CG4859 antikoerper, Dm1-MMP antikoerper, Dmel\\CG4859 antikoerper, MMP-1 antikoerper, MMP1 antikoerper, Mmp 1 antikoerper, dMMP1 antikoerper, dm1-MMP antikoerper, dmmp1 antikoerper, l(2)k04809 antikoerper, mmp1 antikoerper, Mmp1 antikoerper, Mcol-A antikoerper, Mcola antikoerper, col4 antikoerper, mmp18 antikoerper, Clgn antikoerper, matrix metallopeptidase 1 antikoerper, Matrix metalloproteinase 1 antikoerper, matrix metalloproteinase 1 antikoerper, matrix metallopeptidase 1 (interstitial collagenase) antikoerper, matrix metallopeptidase 1a (interstitial collagenase) antikoerper, matrix metallopeptidase 1 S homeolog antikoerper, interstitial collagenase antikoerper, matrix metallopeptidase 8 L homeolog antikoerper, MMP1 antikoerper, Mmp1 antikoerper, RB11133 antikoerper, Mmp1a antikoerper, mmp1.S antikoerper, LOC100727966 antikoerper, mmp8.L antikoerper
- Hintergrund
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Name/Gene ID: MMP1
Subfamily: Metallopeptidase M10A
Family: Protease
Synonyms: MMP1, CLG, Fibroblast collagenase, Matrix metalloprotease 1, MMP-1, Interstitial collagenase, Matrix metalloproteinase 1, Matrix metalloproteinase-1 - Gen-ID
- 4312
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