TIMP1 Antikörper
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- Target Alle TIMP1 Antikörper anzeigen
- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TIMP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func)
- Spezifität
- Recognizes human TIMP-1 (Tissue Inhibitor of Metalloproteinase -1), a secreted glycoprotein and member of the protease inhibitor I35 (TIMP) family, which is expressed by a wide range of cells, including microvascular endothelial cells, smooth muscle cells, mesangial cells, and some fibroblasts. TIMP-1 acts as a natural extracellular inhibitor of MMPs (matrix metalloproteinases), a group of peptidases involved in degradation of the extracellular matrix, and is also involved in erythropoiesis, through the simulation of the proliferation/differentiation of erythroid progenitors. Studies have shown that a correlation between localized concentrations of TIMP-1 and TIMP-3, may determine cell fate, and that increased expression of TIMP-1, may act as an inhibitor/suppressor of invasive cell growth.
- Aufreinigung
- Affinity purified
- Immunogen
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Recombinant human TIMP-1.
Type of Immunogen: Recombinant protein - Isotyp
- IgG
- Top Product
- Discover our top product TIMP1 Primärantikörper
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- Applikationshinweise
- Approved: ELISA (0.5 - 2 μg/mL), Func, IHC, IHC-P, WB (0.1 - 0.2 μg/mL)
- Kommentare
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Target Species of Antibody: Human
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Rekonstitution
- Distilled water
- Konzentration
- Lot specific
- Buffer
- PBS
- Handhabung
- Aliquot to avoid repeated freezing and thawing.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.
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- Target
- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
- Andere Bezeichnung
- TIMP1 (TIMP1 Produkte)
- Synonyme
- TIMP-1 antikoerper, TIMP1 antikoerper, DKFZp468A0912 antikoerper, CLGI antikoerper, EPA antikoerper, EPO antikoerper, HCI antikoerper, TIMP antikoerper, Timp antikoerper, Clgi antikoerper, TIMP metallopeptidase inhibitor 1 antikoerper, tissue inhibitor of metalloproteinase 1 antikoerper, TIMP1 antikoerper, Timp1 antikoerper
- Hintergrund
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Name/Gene ID: TIMP1
Synonyms: TIMP1, CLGI, EPA, HCI, Metalloproteinase inhibitor 1, TIMP-1, Collagenase inhibitor - Gen-ID
- 7076
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