VTI1B Antikörper (AA 1-206)

Produktnummer ABIN1742350

Produktdetails anti-VTI1B Antikörper

Target: VTI1B (Vesicle Transport through Interaction with T-SNAREs Homolog 1B (VTI1B))

Bindungsspezifität: AA 1-206

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VTI1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Spezifität: Specific for vti1b.

Aufreinigung: antiserum

Immunogen: Recombinant rat vti1b (aa 1-206).

Anwendungsinformationen

Applikationshinweise: WB: 1 : 1000 (AP staining)
ICC: 1 : 1000
IHC-P: 1 : 250

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS

Handhabung: Crude antisera are more robust than monoclonals. With anti-microbials added, they may be stored at 4 °C.
Serum does not contain active proteases, in fact, serum itself contains a powerful cocktail of protease inhibitors. Frozen storage (-20 °C),however, is preferable.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.

Referenzen für anti-VTI1B Antikörper (ABIN1742350)

Bhat, Friedmann, Knörck, Hoxha, Leidinger, Backes, Meese, Keller, Rettig, Hoth, Qu, Schwarz: "Syntaxin 8 is required for efficient lytic granule trafficking in cytotoxic T lymphocytes." in: Biochimica et biophysica acta, Vol. 1863, Issue 7 Pt A, pp. 1653-64, (2016) (PubMed).

Golebiewska, Harper, Williams, Savage, Goggs, Fischer von Mollard, Poole: "Syntaxin 8 regulates platelet dense granule secretion, aggregation, and thrombus stability." in: The Journal of biological chemistry, Vol. 290, Issue 3, pp. 1536-45, (2015) (PubMed).

Ramirez, Khvotchev, Trauterman, Kavalali: "Vti1a identifies a vesicle pool that preferentially recycles at rest and maintains spontaneous neurotransmission." in: Neuron, Vol. 73, Issue 1, pp. 121-34, (2012) (PubMed).

Offenhäuser, Lei, Roy, Collins, Stow, Murray: "Syntaxin 11 binds Vti1b and regulates late endosome to lysosome fusion in macrophages." in: Traffic (Copenhagen, Denmark), Vol. 12, Issue 6, pp. 762-73, (2011) (PubMed).

Qu, Pattu, Junker, Schwarz, Bhat, Kummerow, Marshall, Matti, Neumann, Pfreundschuh, Becherer, Rieger, Rettig, Hoth: "Docking of lytic granules at the immunological synapse in human CTL requires Vti1b-dependent pairing with CD3 endosomes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 12, pp. 6894-904, (2011) (PubMed).

Fraldi, Annunziata, Lombardi, Kaiser, Medina, Spampanato, Fedele, Polishchuk, Sorrentino, Simons, Ballabio: "Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders." in: The EMBO journal, Vol. 29, Issue 21, pp. 3607-20, (2010) (PubMed).

Details zu VTI1B

Target: VTI1B (Vesicle Transport through Interaction with T-SNAREs Homolog 1B (VTI1B))

Andere Bezeichnung: Vti1b (VTI1B Produkte)

Synonyme: VTI1 antikoerper, VTI1-LIKE antikoerper, VTI1L antikoerper, VTI2 antikoerper, v-SNARE antikoerper, vti1-rp1 antikoerper, AU015348 antikoerper, GES30 antikoerper, MVti1b antikoerper, SNARE antikoerper, Vti1-rp1 antikoerper, zgc:63525 antikoerper, VTI1B antikoerper, vesicle transport through interaction with t-SNAREs 1B antikoerper, vesicle transport through interaction with t-SNAREs 1B pseudogene antikoerper, VTI1B antikoerper, Vti1b antikoerper, vti1b antikoerper, LOC461624 antikoerper