TNFSF13 Antikörper (AA 196-210)

Produktnummer ABIN1731914

Produktdetails anti-TNFSF13 Antikörper

Target: TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))

Bindungsspezifität: AA 196-210

Reaktivität: Human, Drosophila melanogaster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFSF13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Reacts with the extracellular domain 2 of human APRIL. Cross-reacts with drosophila protein.

Aufreinigung: Purified

Immunogen: Peptide corresponding to aa 196-210 of human APRIL

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB(2 - 4 μg/mL) IHC(10 μg/mL)

Positive control: HL60 or Jurkat cell

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Details zu TNFSF13

Target: TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))

Andere Bezeichnung: APRIL (TNFSF13 Produkte)

Synonyme: APRIL antikoerper, CD256 antikoerper, TALL-2 antikoerper, TALL2 antikoerper, TRDL-1 antikoerper, ZTNF2 antikoerper, 2310026N09Rik antikoerper, April antikoerper, Tall2 antikoerper, Trdl1 antikoerper, SLAN antikoerper, ANP32B antikoerper, april antikoerper, tnf13 antikoerper, TNLG7B antikoerper, TNF superfamily member 13 antikoerper, tumor necrosis factor (ligand) superfamily, member 13 antikoerper, acidic leucine-rich nuclear phosphoprotein 32 family member B antikoerper, TNFSF13 antikoerper, Tnfsf13 antikoerper, LOC494442 antikoerper, tnfsf13 antikoerper

Hintergrund: This antibody recognizes human APRIL (A Proliferation-Inducing Ligand), a novel member of the TNF family. Two receptors for APRIL, TACI and BCMA were recently identified. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-κB, and induces cell death. APRIL is associated with autoimmune diseases and cancer.

Tumor necrosis factor ligand superfamily member 13 A proliferation-inducing ligand, APRIL TNF- and APOL-related leukocyte expressed ligand 2, TALL-2 TNF-related death ligand 1, TRDL-1 CD_antigen: CD256 Gene name: TNFSF13, APRIL, TALL2, ZTNF2, UNQ383/PRO715

Gen-ID: 8741

UniProt: O75888

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response