NMDAR3A + 3B Antikörper

Produktnummer ABIN1721533

Produktdetails anti-NMDAR3A + 3B Antikörper

Target: NMDAR3A + 3B (GRIN3A/B) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 3A/B (GRIN3A/B))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NMDAR3A + 3B Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP), Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: Reacts with human Glutamate NMDA Receptor NR3A/B Subunit. Cross-reacts with mouse and rat protein. Do not cross-react with subunits NR1 or NR2A-D.

Aufreinigung: Purified (protein G)

Immunogen: Fusion protein of NR3A aa sequence 780-914 from the extracellular IIIIV loop.

Klon: K35-40

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC(1 - 10 μg/mL) WB (1 - 10 μg/mL)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, pH 7.4.

Handhabung: Dilute in PBS or medium that is identical to that used in the assay system.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NMDAR3A + 3B

Target: NMDAR3A + 3B (GRIN3A/B) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 3A/B (GRIN3A/B))

Abstract: GRIN3A/B Produkte

Hintergrund: Two new subunits of the NMDA subtype of glutamate receptor (NMDAR) have been identified, NR3A and NR3B, with NR3B likely being the final member of the NMDAR family. These subunits show high sequence homology, although different distribution patterns: NR3B is expressed predominately in motor neurons, while NR3A is more widely distributed. When expressed in Xenopus oocytes, NR3A or NR3B assemble with NR1 to form excitatory glycine receptors that are unaffected by glutatmate.

Glutamate receptor ionotropic, NMDA 3A, GluN3A N-methyl-D-aspartate receptor subtype 3A, NMDAR3A, NR3A NMDAR-L

Gen-ID: 116443

UniProt: Q8TCU5