DNAJC5 Antikörper (AA 1-100)

Produktnummer ABIN1715067

Produktdetails anti-DNAJC5 Antikörper

Target: DNAJC5 (DnaJ (Hsp40) Homolog, Subfamily C, Member 5 (DNAJC5))

Bindungsspezifität: AA 1-100

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNAJC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CSP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu DNAJC5

Target: DNAJC5 (DnaJ (Hsp40) Homolog, Subfamily C, Member 5 (DNAJC5))

Andere Bezeichnung: CSP (DNAJC5 Produkte)

Synonyme: CG6395 antikoerper, CSP antikoerper, CSP32 antikoerper, Cys antikoerper, D-CSP antikoerper, D.M.CSP antikoerper, DCSP-1 antikoerper, Dcsp antikoerper, Dmel\\CG6395 antikoerper, MAB ab49 antikoerper, ab49 antikoerper, anon-WO02059370.50 antikoerper, csp antikoerper, csp29 antikoerper, csp32 antikoerper, l(3)03988 antikoerper, Csp antikoerper, GB10835 antikoerper, cb995 antikoerper, dnajc5 antikoerper, zgc:92898 antikoerper, dnajc5a antikoerper, DNAJC5 antikoerper, CLN4 antikoerper, CLN4B antikoerper, DNAJC5A antikoerper, NCL antikoerper, 2610314I24Rik antikoerper, AU018536 antikoerper, csp-beta antikoerper, Cysteine string protein antikoerper, cysteine string protein antikoerper, dnaJ homolog subfamily C member 5 antikoerper, DNAJ/TPR domain-containing protein DNAJC7 family protein antikoerper, DnaJ (Hsp40) homolog, subfamily C, member 5aa antikoerper, DnaJ heat shock protein family (Hsp40) member C5 gamma L homeolog antikoerper, DnaJ heat shock protein family (Hsp40) member C5 gamma antikoerper, DnaJ (Hsp40) homolog, subfamily C, member 5 antikoerper, DnaJ heat shock protein family (Hsp40) member C5 antikoerper, DnaJ heat shock protein family (Hsp40) member C5 S homeolog antikoerper, Csp antikoerper, LOC724965 antikoerper, SJAG_04371 antikoerper, dnajc5aa antikoerper, dnajc5g.L antikoerper, Tsp_06120 antikoerper, dnajc5g antikoerper, DNAJC5 antikoerper, Dnajc5 antikoerper, dnajc5.S antikoerper

Hintergrund:

Synonyms: CLN 4, CLN4, CLN4B, CSP, cysteine string protein alpha, Cysteine string protein, DJC5, DnaJ Hsp40 homolog subfamily C member 5, DnaJ homolog subfamily C member 5, DNAJC 5, Dnajc5, DNAJC5A, DNJC5_HUMAN, NCL.

Background: Cysteine string proteins (CSPs) are synaptic vesicle-associated, secretory vesicle proteins that are involved in Ca2+-regulated exocytosis of synaptic vesicles and modulation of presynaptic transmembrane calcium fluxes in neuroendocrine and endocrine cell types. CSP contains a J-domain that binds HSP 70/HSC 70 chaperone ATPases and a membrane-targeting, palmitoylated cysteine-rich string region. CSPs may act as molecular chaperones in synapses, and mediate conformational folding of components of the vesicular exocytotic machinery. CSP is involved in the fine tuning of neurotransmission through its interaction with receptor-coupled trimeric GTP binding proteins (G proteins) and N-type Ca2+ channels. Two variants of CSP have been described: CSP1, and the 31 amino acid, C-terminally truncated isoform, CSP2. Subcellular fractionation of insulinoma cells shows CSP1 in granular fractions, while the membrane and cytosol fractions contain predominantly CSP2. The fractions also contain additional proteins, presumably CSP dimers. Furthermore, in various mammalian cell lines (including rat brain) CSP1 expression predominates CSP2 expression.

Gen-ID: 80331

Pathways: Synaptic Vesicle Exocytosis