DROSHA Antikörper (AA 751-850)

Produktnummer ABIN1714522

Produktdetails anti-DROSHA Antikörper

Target: DROSHA (Drosha, Ribonuclease Type III (DROSHA))

Bindungsspezifität: AA 751-850

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DROSHA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Drosha/RNase III Drosha

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu DROSHA

Target: DROSHA (Drosha, Ribonuclease Type III (DROSHA))

Andere Bezeichnung: Drosha/RNase 3 Drosha (DROSHA Produkte)

Synonyme: im:7150667 antikoerper, zgc:158612 antikoerper, ETOHI2 antikoerper, HSA242976 antikoerper, RANSE3L antikoerper, RN3 antikoerper, RNASE3L antikoerper, RNASEN antikoerper, 1110013A17Rik antikoerper, AI874853 antikoerper, Etohi2 antikoerper, Rn3 antikoerper, Rnasen antikoerper, RGD1307626 antikoerper, ribonuclease type III, nuclear antikoerper, Ribonuclease 3 antikoerper, ribonuclease 3 antikoerper, drosha ribonuclease III antikoerper, drosha, ribonuclease type III antikoerper, rnasen antikoerper, Thicy_0885 antikoerper, Sinme_0866 antikoerper, Isova_2087 antikoerper, Sphch_0770 antikoerper, DROSHA antikoerper, Drosha antikoerper

Hintergrund:

Synonyms: DROSHA, Drosha double stranded RNA specic endoribonuclease, Drosha ribonuclease type III, Etohi2, HSA242976, Nuclear RNase III Drosha, p241, Protein Drosha, Putative protein p241 which interacts with transcription factor Sp1, Putative ribonuclease III, RANSE3L, Ribonuclease 3, Ribonuclease III, Ribonuclease III nuclear, Ribonuclease type III nuclear, RibonucleaseIII, RN 3, RN3, RNase 3, RNase III, RNase3, RNASE3L, RNaseIII, RNASEN, RNC_HUMAN.

Background: The ribonuclease III superfamily represents a structurally distinct group of double-strand-specific endonucleases with essential roles in RNA maturation, RNA decay, and gene silencing. Initial cleavage of microRNAs is catalysed by Drosha, a nuclease of the RNase III family, which acts on primary miRNA transcripts (pri-miRNAs) in the nucleus. Human Drosha is a component of two multi-protein complexes. The larger complex contains multiple classes of RNA-associated proteins including RNA helicases, proteins that bind double-stranded RNA, novel heterogeneous nuclear ribonucleoproteins and the Ewing's sarcoma family of proteins. The smaller complex is composed of Drosha and the double-stranded-RNA-binding protein, DGCR8.

Gen-ID: 29102

Pathways: Regulatorische RNA Pathways