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C1orf85 Antikörper (AA 51-150) (Cy5.5)

C1ORF85 Reaktivität: Human WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Cy5.5
Produktnummer ABIN1706577
  • Target Alle C1orf85 (C1ORF85) Antikörper anzeigen
    C1orf85 (C1ORF85) (Chromosome 1 Open Reading Frame 85 (C1ORF85))
    Bindungsspezifität
    • 14
    • 2
    • 1
    AA 51-150
    Reaktivität
    • 14
    • 3
    • 1
    Human
    Wirt
    • 16
    • 1
    Kaninchen
    Klonalität
    • 17
    Polyklonal
    Konjugat
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser C1orf85 Antikörper ist konjugiert mit Cy5.5
    Applikation
    • 17
    • 12
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human C1orf85
    Isotyp
    IgG
    Top Product
    Discover our top product C1ORF85 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    C1orf85 (C1ORF85) (Chromosome 1 Open Reading Frame 85 (C1ORF85))
    Andere Bezeichnung
    C1orf85 (C1ORF85 Produkte)
    Synonyme
    NCU-G1 antikoerper, C1orf85 antikoerper, 0610031j06rik antikoerper, AB027141 antikoerper, CA085 protein antikoerper, glycosylated lysosomal membrane protein antikoerper, glmp antikoerper, GLMP antikoerper, Glmp antikoerper
    Hintergrund

    Synonyms: C1orf85, Chromosome 1 open reading frame 85, Lysosomal protein NCU-G1, NCUG1_HUMAN, PSEC0030, UNQ2553/PRO6182.

    Background: C1orf85, also known as Lysosomal protein NCU-G1, is a 406 amino acid single-pass membrane protein that is highly glycosylated on its amino-terminal end. Transcription of the gene encoding C1orf85 is activated by TFEB, a transcription factor that specifically recognizes and binds E-box sequences. There are two isoforms of C1orf85 that are produced as a result of alternative splicing events. The C1orf85 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.

    Gen-ID
    112770
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